What Does mif Mean?
What Does mif Mean?
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Some the latest reports implicate MIF with development of large glucose-induced advert. AGEs (State-of-the-art glycation endproducts) are neurotoxic, foster the deposition of Aβ and the hyperphosphorylation of tau protein along with the expression of proinflammatory mediators in glial cells [83, eighty four]. It has been shown that AGEs promoted the expression of MIF and aggravated the neuroinflammatory response at the cell stage [85]. In PC12 cells, (an AD-mobile design), ISO‑one lessened AGE‑mediated injury by lowering the expression of neuroinflammatory mediators. Beforehand, MIF has actually been found for being glycated and oxidized in AD Mind homogenates.
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